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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02b55e83a16f0611cb5f755ceef546d2a8bd64d026a275b753c23416b054f272' 
  AND token = 'tzGNj/GY65RZgkiVDii6iY5aaUQjVaxSqctHhwaKEB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}