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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e34d6854f2a1ef7d7056418c250389fc18604c69417f4df3ed230ee29f6a09b' 
  AND token = '73siST3VR56+oRIcYy/h/fD7H2H7IHhcXrVez538cTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}