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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e188e99d4f7c8a5b8ea34c56c97ce2809730a5566e8d756d9c007d77ffc5ee2f' 
  AND token = 'q50DcJgr0969HqIk3jfZdwI29MT+S4L+QqxQLSr8lsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}