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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4da6820dc4520d6f495601e2c96961c53f1c73dd51838f7abcae45bdff6c9049' 
  AND token = '1UMu4co4wgwP146m/ctxK4qBOuWMjswl2rcZCFrD4yo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}