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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1145147369715caf7ecdc02be7671499c9e127fc7ab7d5a0f2bf1005d27af26' 
  AND token = 'crVEIMudRb/IOTJTRLHfUN7Wg/+d7lrNiHSUQZ4qmZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}