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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16b5ba962f2fca3e69cb768ce5546a53f0f40b02c6542b926cfea321526a83cc' 
  AND token = '+7ZtYZXJJLK9IanHh6d6a+bs5EJdfsxC69ShpYkc1U4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}