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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b6a59ce8b742131dd4381ece0a4203461f59324a109632eb3c9b40f3aa0de64' 
  AND token = 'cJOY8sJ2Ern2dJRFqitpYslGsyJf/7p9qU+lP9c42nU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}