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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '925a18b226f29d938a7041078a338b57b7921f26ca5bedb59d8116ad0fbf1d72' 
  AND token = 'TZvWlkaGLvj/7sesKWtMReq0CrPzra3QWZuZM6R84y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}