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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65e797ab9dac14e0d5d58564618f64c1f0a17c6c98ae31c8c243863d3c99f4e4' 
  AND token = 'a+bnEaxb/uyVkXP0rOrOYBPaHqiysbBhbPFk1RElOLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}