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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36d6ff1250880019f61d17a39a2f2e10af40063c71595b7518cbc355b40ad557' 
  AND token = '1+WuRJQVmZUh9VEg7bdAk0XGHB2quWQn6RI6E1MnOt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}