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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7eca211e5b78250d4bf70d7427ca0c53fa8110dc6d939396034e8ca0dea8e925' 
  AND token = 'rqMe0LED+0HYTImdDujiHw18vy2XtvTDGjU+8k5MGIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}