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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ad6100f07ad1725d3be7bd143bf32dd28cf1a0f534c2f625c9684f6cd7c94e6' 
  AND token = 'dk59JOhBDCDeMiXg+q5yG7YXz1L5kihwMo4Rro4jwSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}