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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5844e4839039e05cafff648f10da4065c55b9ca334c9cb7c73a04f321d622f5' 
  AND token = 'a6DLYR7q1kVPPb4QWw8OxxWreskfJV2dm+PkfxhhXoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}