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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '257be9c6adca4ba511202c46b44e879126dac39dda97652c4b69c8a09dda0260' 
  AND token = 'kpsRi2Mo6nLcXhOJLESpmF68DgoU9DZiH1ZXWRosnUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}