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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17ba617fa025bdcb2dcc6498ed4973edb5b88949d1b310ec5b07a75387a95e10' 
  AND token = 'MlPaBMCfs8R7aMdS/dDPEt6aHVpRjfKyIko3yVuA7Lc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}