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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ef3f12612ec5059677df787382942bc29834fc4bdf86ec0c927d0bbaf191af9' 
  AND token = 'Q+Ecv8ZtAnG2l3anbDsPUo/YsH51m4H2rDpFO+uojas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}