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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64debb087ce5a754bd53a1cdaa3f62da724bb3ceeb815cf6111dad75f77b69ba' 
  AND token = 'rC8Tj9PorIk+lChsIOvoO7jCSFA+Bn0w+rqg04RN5DI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}