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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73ddf310fa52c57e8d6646c0285e836e5dd0b6f5db8ed0629d66e8a1f6221bad' 
  AND token = 'eETg+3HOTFPpykIl0HbcvWa+O8h9hClB5G7aK76tUmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}