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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '62e7abaed3c704d0945c68f1f066c26c6fad739ee0ba1fe0854ba34f7aa72077' 
  AND token = '1NyodKB46gEr20PjRevjIRk04qB7VVaTVmLoX5w343A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}