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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce4d0ca99a318e8c4c8d045db7a72e1a750a9ec3fe9185a380e659c8ad33a813' 
  AND token = 'tPFAZHqjiYzMPn5vmwy+yLZHbsj1XlrQGGuJWkYVrzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}