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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd15a33339f95a4a577bc5c000a4d31d305c5d06dfe9f44f1fea984d7e5478a1' 
  AND token = 'rHzUHhiop4dd+SydQ1Sk8ypKg6KcKW5JamrOtO5u0gw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}