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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b4610708f38199da6131a5d6f3024ef3b46cd1fd8186998cb7a9ae92e3b10a5' 
  AND token = 'AO8K9WXfivF0rzTb0IU4rPlGtxpmg1PZ5m0mql+m56I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}