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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '927b17d26fa919bb181a14df54cd06c7d8641a97bd2a27a8210c714960faf8e8' 
  AND token = '21IWGP+KnXTHT5gnxOfiisH135OTHUqb8dEA6MfYwEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}