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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22a2802287e03fb40400c46225337c5036e1cb6e6c6865798c6bc70851afb38a' 
  AND token = 'VXoD/nyxLGFw2dv4A2tS3MQFiEobNYAqezVitOAuKNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}