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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c6d521b320eddc19985d9f728c5aa82186a171cb6dc14ac9f5db370f58a04c5' 
  AND token = 'n5lFh/G5d3nHDbxT5z4v1tIhAtQhQRgSgb6n83pt0tk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}