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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8684e1f4d6c35d725d2d1ed47cbc10d73273f4b763c85d9265f7adbc4c0bf21' 
  AND token = 'PF8OrwavMgLr9vd9b2TEm21xJlI/Dy9bkOWrMPXvqmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}