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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6b09a116c826a7f0480d62a3f2ead356c0e0aa0d1c9dd8be47541ea2a9eb853' 
  AND token = 'tyMeMybPxYDDiEa+8zVR4FVSvQGyXydwW+O3uTaAQ7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}