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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '046f2a6b9344411098a91ad8384b26d10a22a59845be2b169805f4cf2b8841f2' 
  AND token = 'CoLtMNCqzyXVwtMtdukcvODzq2PwJi6jU8ilLp68z0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}