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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69eaea32681b6ac0334777a44eb47db461221cb7b47edfa39c60979356d1de28' 
  AND token = 'UPR/7GXScFJ9Lsl+bwOO44c9X3/gF0fRXUY7NyfVCzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}