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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72d21aab86c6e506a12e0321540b89a28f14b10184731218902b0ebe0f345aa2' 
  AND token = '8Ly6XfZMA9wgs+g+aq1HPWbzSokYuKgTCSYycyuY/yw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}