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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae754cf2e470f817902afff2832dc8235fc9f15900c9f43b385b35347aab2b94' 
  AND token = 'kXVJdp81kP1pEfYrhEockBr9YMXTHx6eXzuVkio0WT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}