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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09e71ea80627f304e5c2e5a1f33e339c2fa8b018af7ba24132e87f6b64b7acea' 
  AND token = 'VigQkrkMyaxR/PyC/X+CUFwTB1Oyz+BRVIiyKxfsB1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}