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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9ed8922e1a62b520f2078245766f9c57dbdc53559b7b8141f5a7f99baca28a0' 
  AND token = 'KUIeM8oT4m3MGkAU76mCy/m+nDkUUOLUcBRTz0rSDnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}