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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22a2345d10164225541a9e286b76cb8991d05390b505d9891566331e66e30bad' 
  AND token = 'KZDRixfnAXL3hQNT3i2FhBR3gWySwikiJsvUY3R6fWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}