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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2131811d0cbaaecd55b0aadc38c3803e37d56849cc721e6ad8fa3b374f87e9cd' 
  AND token = 'dULBXfo6i0JV8x3W2+emVxCzIZF+cEtYvWCuxHqH7hY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}