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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e70faee0887ce667a0192b0c1b09a8b46c06bfd42ac7481c42750040480a0e6' 
  AND token = 'QxJTbCEIlsYWBxItCJ8dD9z7lqdAtN1I2PwjbKxxvdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}