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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a229484afd479ab2cf762fd715785dd752ba12271b014e9a2a02740a3d5018ef' 
  AND token = 'tbIPVCZ6by92/GLyRGo+jV0bWyTNa89kc6pUaPTvLl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}