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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '462e66ee638c4106453700bd7712a2767ee1097d464a9f0f095d3f2a2f8b6d61' 
  AND token = 'lxnTM995JC2QoUCTCKiwyjhnMAk+eGBQnZ53MgVkw3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}