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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be32ef939bf52bd2ccfa6a604dd7387e7224a0c80d1cd55de5abff9d1c735a46' 
  AND token = 'MfWiotwwJD+TZy5gj2SwYt1yhyn63SZ7ESLFqM943U4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}