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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6804ed3d8c63b2db30b156c402ca4a19056e92172869a60e920025fe3ebe6165' 
  AND token = '2ggOFCsX4b6hBIgWcgOeIyQeBpmVrUykybuZV5hMzsw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}