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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8c46787472a8969340cd3bcfa9f5c24abcca656909a8794bdadc2bddf7c0010' 
  AND token = 'vaD59yqCVBhkpPchY8KPJTyBU9O+lP4O9c5Yrs3HHa0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}