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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c294c4325177232d143f69e0d77c209359937840d23988d83c713c752aa780c2' 
  AND token = 'n49W0Bt7mKQHgln+wFAxfSPGpTwugvWXE+eU/KbK5Hk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}