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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0c6459e62e79a6ac6c423045270e3629e3ef2620d65b188073fbaefa84787c4' 
  AND token = 'a6yev2oOm2JPa1nKXhN+h6Vrw+dm1NkKHanIlmhSVSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}