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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2de0d56900dcea33dd11bab077c3d021236d6ccc3e511cac40cc9cba1bac5055' 
  AND token = 'DB9wInPiUM9sfGXga4LFzEM5qydtTqCywG+doWjr/bk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}