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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29162860b5a9abd4b7a2f3027c6ffa2ec17f049ae4dbffd6257304d0944b03c6' 
  AND token = '52nQsHgBdyntiKWFPr5LpH4QgNMK681WNPY5WwH4NGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}