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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ad80ec3d7fb02052fb68865875f783b4c6ae549b0592a91ac42ea14cab31ac1' 
  AND token = 'ujcYsUtV0vyaO2bz1R+uRZZ8onjQXiNDs1T6PpaqXCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}