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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cb33d3aed2eb8c1398e4584601255592d6c59ab4d35da13e19a384e5c9261ae' 
  AND token = 'Zpl9Km5dQcA/HhDqVPk07XQJlniJB5G8sQ6/5cH0LXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}