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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47d2e48641c361eb88db6f94e680b333fbceeaa8ad1c254315fe21835d92a21a' 
  AND token = '8hNiqKmkN73+8NlbXv/VXi4R6M6+lzxcNMKBjqpqE8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}