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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2df9875b118b60032881bb2d914283c9f8bf39fa335e37d361004693f74a1f1b' 
  AND token = 'sQk6Onv/HJ6OzKz67AFo32SMf7NFhfxXFXyyf7W9ceA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}