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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f260a18638418390d176eeba0e082990a5abf3e97fd1b8b816268c33185f5406' 
  AND token = '0NsFhW9255yaMr+4eNSBBis1cIaHo9h8/rc+DXwsPHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}